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Creatine kinase is a dimer occurring in various in three isoenzymic forms, depending on the particular combination of its non-identical subunits: BB (brain type); MM (skeletal type); and MB(hybrid type). Creatine kinase-MB isoenzyme is released into circulation later than myoglubin, reaching abnormal levels within 4 to 6 hours after onset of symptoms, it reaches its highest level with a typical range of 39-185 ng/ml after about 18 to 24 hours, and returns to normal in about 2 to 3 days. CK-MB is widely recognized as the traditional marker for the diagnosis of acute myocardial infarction (AMI). K-MB test is a sandwich immunoassay. When serum sample is added to sample pad, it moves through the conjugate pad and mobilizes gold anti-CK-MB conjugate that is coated on the conjugate pad. The mixture moves along the membrane by capillary action and reacts with anti-CK-MB antibody that is coated on the test region. If CK-MB is present at levels of 7.0 ng/ml or greater, the result is the formation of a colored band in the test region. If there is no CK-MB in the sample, the area will remain colorless. The sample continues to move to the control area and forms a pink to purple color, indicating the test is working and the result is valid.
It is designed for qualitative determination of CK-MB in human serum specimens as an aid in the diagnosis of myocardial infarction.
It is designed for qualitative determination of CK-MB in human serum specimens as an aid in the diagnosis of myocardial infarction.
CatalogRCM-020C
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ProductCK-MB
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FormatCassette
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Specimen *S/P
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Kit Size20 est
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* whole blood test could be conducted with assistant of assay buffer; but it may not work for every patient due to blood coagulation
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or sales@biogatelab.com for more information about sample, order, product information and business cooperation.
or sales@biogatelab.com for more information about sample, order, product information and business cooperation.