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Dengue viruses, transmitted by Aedes aegypti and Aedes albopictus mosquitoes, are widely distributed throughout the tropical and subtropical areas of the world. There are four known distinct serotypes (dengue virus 1, 2, 3, and 4). In children, infection is often sub-clinical or causes a self-limited febrile disease. However, if the patient is injected a second time with a different serotype, a more severe disease, dengue hemorrhagic fever or dengue shock syndrome, is more likely to occur. Dengue is considered to be the most important arthropod-borne viral disease due to the human morbidity and mortality associated with it. NS1 is a highly-conserved glycoprotein that is present at high concentrations in the sera of dengue-infected patients during the early clinical phase of the disease. NS1 antigen is found from the first day and up to 9 days after the onset of fever in samples of primary or secondary dengue infected patients. Usually IgM does not become detectable until 5 to 10 days after the onset of illness in cases of primary dengue infection and until 4 to 5 days after onset of illness in secondary infections. In primary infections, IgG appears the 14th day and persist for life. Secondary infections show that IgG rise within 1-2 days after the onset of symptoms and induce IgM response after 20 days of infection.
CatalogRDN-011C
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ProductDengue NS1
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FormatCassette
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Specimen *WB/S/P
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Kit Size20 test
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* whole blood test could be conducted with assistant of assay buffer; but it may not work for every patient due to blood coagulation
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or sales@biogatelab.com for more information sample, order, product information and business cooperation.